Clinically meaningful itch relief demonstrated in children
6-11 YEARS
Itch reduction at Week 16 (secondary endpoint)1-3,a,b
aFull Analysis Set includes all subjects randomized.
bIn the primary analyses of the efficacy endpoints, subjects who received rescue treatment or with missing data were considered nonresponders.
cAt Day 1, subjects (baseline weight <30 kg) received 600 mg of DUPIXENT.
dAt Day 1, subjects (baseline weight ≥30 kg) received 400 mg of DUPIXENT.
Pruritus NRS assesses the average itch intensity over the previous 24 hours4
It is a patient-reported measure that uses a 0- to 10-point scale, with which patients are asked:
“On a scale of 0 to 10, how would you rate your itch overall (on average) during the previous 24 hours?”
0
None
1
2
3
4
5
6
7
8
9
10
The Worst
Imaginable
A reduction of at least 4 points in pruritus NRS from baseline is a clinically meaningful change.1
Dosage and Administration
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