
Available in a 300 mg pre-filled pen or 300 mg pre-filled
syringe for subcutaneous injection
ONE DOSAGE REGIMEN IN ADULTS1
Nodularis
18+ YEARS
Initial loading dose:
600 mg
2 x 300 mg
Followed by:
300 mg Q2W
1 x 300 mg
- DUPIXENT is administered by subcutaneous injection and intended for use under the guidance of a healthcare provider1
- Rotate injection site with each injection1
- Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT
prior to use, according to
the Instructions for Use1 - Consider completing all age-appropriate vaccinations as recommended by current immunization guidelines prior
to initiating
treatment with DUPIXENT1 - If an every-other-week dose is missed, instruct the patient to administer the injection
within 7 days from the missed dose and then
resume their original schedule. If the missed dose is not administered within 7 days, instruct the patient to wait until the next dose
on the original schedule1
Q2W, once every 2 weeks
At-home or in-office administration options
Important
administration
instructions
- Patients and/or caregivers should read the Instructions for Use prior to injecting1
- Instruct patients and/or caregivers to administer subcutaneous injection into the thigh or abdomen, except for the 2 inches (5 cm) around the navel1
- The upper arm can also be used if a caregiver administers the injection1
- It is important to rotate the injection site with each injection. DO NOT inject DUPIXENT into skin that is tender, damaged, bruised, or scarred1
- For the initial dose, patients and/or caregivers should administer each DUPIXENT injection at a different injection site1
See the Instructions for Use for more detailed instructions on the preparation and administration of DUPIXENT
Pre-Filled Pen
Instructions for Use - 300 mgPre-Filled Syringe
Instructions for Use - 300 mgSupplemental Injection Training
VIEW PATIENT VIDEOSPreparation for Use1
Before injection, instruct patients and/or caregivers to remove DUPIXENT from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.
- 45 minutes for the 300 mg/2 mL pre-filled syringe or pre-filled pen
Patients and/or caregivers should inspect DUPIXENT for particulate matter and discoloration prior to administration.
- Do not use if the liquid contains visible particulate matter or is discolored or cloudy (other than clear to slightly opalescent, colorless to pale yellow)
Patients and/or caregivers should discard any unused product remaining in the pre‑filled syringe or pre-filled pen in accordance with local requirements.
Storage and Handling1
- DUPIXENT is sterile and preservative-free. Patients and/or caregivers should discard any unused portion
- Patients and/or caregivers should store DUPIXENT by refrigerating at 36 °F to 46 °F (2 °C to 8 °C) in the original carton to protect from light
- If necessary, DUPIXENT may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. DUPIXENT should not be stored
above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded - DUPIXENT should not be exposed to heat or direct sunlight
- Do NOT freeze. Do NOT shake
- Any unused medicinal product or waste material should be disposed of in accordance with local requirements
