Available in a 300 mg pre-filled pen or 300 mg pre-filled
syringe for subcutaneous injection

ONE DOSAGE REGIMEN IN ADULTS1

Dosage for Prurigo
Nodularis
18+ YEARS

Initial loading dose:

600 mg

2 x 300 mg

  • DUPIXENT is administered by subcutaneous injection and intended for use under the guidance of a healthcare provider1
  • Rotate injection site with each injection1
  • Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use, according to
    the Instructions for Use1
  • Consider completing all age-appropriate vaccinations as recommended by current immunization guidelines prior to initiating
    treatment with DUPIXENT1
  • If an every-other-week dose is missed, instruct the patient to administer the injection within 7 days from the missed dose and then
    resume their original schedule. If the missed dose is not administered within 7 days, instruct the patient to wait until the next dose
    on the original schedule1

Q2W, once every 2 weeks

At-home or in-office administration options

Important
administration
instructions

  • Patients and/or caregivers should read the Instructions for Use prior to injecting1
  • Instruct patients and/or caregivers to administer subcutaneous injection into the thigh or abdomen, except for the 2 inches (5 cm) around the navel1
  • The upper arm can also be used if a caregiver administers the injection1
  • It is important to rotate the injection site with each injection. DO NOT inject DUPIXENT into skin that is tender, damaged, bruised, or scarred1
  • For the initial dose, patients and/or caregivers should administer each DUPIXENT injection at a different injection site1

See the Instructions for Use for more detailed instructions on the preparation and administration of DUPIXENT

Pre-Filled Pen

Instructions for Use - 300 mg

Pre-Filled Syringe

Instructions for Use - 300 mg

Supplemental Injection Training

VIEW PATIENT VIDEOS

Preparation for Use1

Before injection, instruct patients and/or caregivers to remove DUPIXENT from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.

  • 45 minutes for the 300 mg/2 mL pre-filled syringe or pre-filled pen

Patients and/or caregivers should inspect DUPIXENT for particulate matter and discoloration prior to administration.

  • Do not use if the liquid contains visible particulate matter or is discolored or cloudy (other than clear to slightly opalescent, colorless to pale yellow)

Patients and/or caregivers should discard any unused product remaining in the pre‑filled syringe or pre-filled pen in accordance with local requirements.

Storage and Handling1

  • DUPIXENT is sterile and preservative-free. Patients and/or caregivers should discard any unused portion
  • Patients and/or caregivers should store DUPIXENT by refrigerating at 36 °F to 46 °F (2 °C to 8 °C) in the original carton to protect from light
  • If necessary, DUPIXENT may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. DUPIXENT should not be stored
    above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded
  • DUPIXENT should not be exposed to heat or direct sunlight
  • Do NOT freeze. Do NOT shake
  • Any unused medicinal product or waste material should be disposed of in accordance with local requirements

DUPIXENT MyWay®

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