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For your adult patients with prurigo nodularis (PN)

ASSESS WHEN APPROPRIATE PATIENTS MAY BE READY FOR DUPIXENT

ARE YOUR ADULT PN PATIENTS DU FOR A CHANGE?

Ask yourself:

DU THEY
still itch?

DU THEY
still have
Nodules?

If you answer “Yes” to these questions

THEY MAY BE DU FOR DUPIXENT

Among adults with PN

74%

OF PATIENTS

have an inadequate response
to topical steroids1,a

36%

OF PATIENTS

reported visiting their doctor 10
or more times in the past year2,b

aData from a global survey of 92 adult patients diagnosed with PN from 2006 to 2016. Of 49 patients treated with topical corticosteroids not used under occlusion,
only 26.5% reported positive effect on itch. Topical calcineurin inhibitors and topical corticosteroids are not FDA-approved for the treatment of PN.

bData from a global survey between August 13 and September 13, 2019, of 171 adults with PN.

CASE STUDY: A patient with persistent itch
60-year-old male
Case history
  • Itch and firm red bumps developed
    across body regions
  • PCP prescribed medium-potency
    TCS, but nodules and itch
    remained bothersome
  • Saw multiple providers and a
    specialist in past 2 years
Current status
  • Medium- to high-potency TCS as needed
  • Nodules remain and itch is near-constant
  • Frustrated that people always tell him to stop
    scratching

Story inspired by people who
suffer from PN.
PCP, primary care physician;
TCS, topical corticosteroids.

Real image of
prurigo nodularis.

CASE STUDY: A patient with visible nodules
52-year-old female
Case history
  • Nodules developed a few months after
    she began experiencing itch
  • Medium-potency TCS provided
    some temporary relief
  • Referred to a specialist after 1 year
    and frequent PCP visits
Current status
  • High-potency TCS daily for past 2 weeks
  • Has taken 2 courses of OCS in past 6 months
  • Still has widespread disease on arms
    and back
  • People always stare, so she covers up as
    much skin as possible year-round

Story inspired by people
who suffer from PN.
OCS, oral corticosteroids;
PCP, primary care
physician; TCS, topical
corticosteroids.

Real image of
prurigo nodularis.