IDENTIFYING PATIENTS

Even when they say they're fine,
many EoE patients remain uncontrolled

Not an actual patient.

Not an actual patient.

My eoe hasn't been as bad, so i try not to complain.

I’M FINE.

George

Not an actual patient.

CLINICAL PRESENTATION

Histology: 67 EOS/HPF
Symptoms: Painful swallowing and feeling like food is getting stuck
Endoscopic features: Furrows, edema, and rings

CURRENT CONCERNS

Reports that symptoms are less severe but still occur
Avoids eating in public and misses out on events that include eating
Taking high-dose PPI for the past three months

_~55_%

of patients failed to achieve histologic response on PPIs^1,a

Patient profiles are representative and are not actual DUPIXENT patients.

^aBased on a meta-analysis of 73 studies comprising 7304 patients with EoE. Histologic response is defined as <15 EOS/HPF.¹

EOS/HPF, eosinophils per high-power field; PPI, proton pump inhibitor.

I HAVE TO WASH every bite down with a gulp of water, but

I’M FINE.

Mark

Not an actual patient.

CLINICAL PRESENTATION

Histology: 73 EOS/HPF
Symptoms: Difficulty with certain foods
Endoscopic features: Furrows, edema, and rings

CURRENT CONCERNS

Reports minimal symptoms, but probing reveals he cuts food into small pieces, drinks excess water, and avoids events that involve eating
Embarrassed to eat around colleagues and friends due to these adaptive behaviors
Worries about the long-term impacts of EoE

_~75_%

of patients rely on at least one adaptive behavior every day^2,b

Patient profiles are representative and are not actual DUPIXENT patients.

^bBased on a survey of 234 patients aged ≥18 years with EoE to assess symptom burden, treatment patterns, and adaptive behaviors used to manage dysphagia; patients enrolled in clinical trials or self-reporting dupilumab use were excluded.²

I usually don't finish my lunch in time because it's hard to swallow, but

I’M FINE.

Kate

Not an actual patient.

ACG guidelines suggest dupixent as a treatment for EoE in appropriate individuals who are nonresponsive to PPI therapy4,c

Patients 12+ years

Quality of evidence: moderate

Strength of recommendation: conditional

Patients 1-11 years

Quality of evidence: low

Strength of recommendation: conditional

ACG, American College of Gastroenterology; PPI, proton pump inhibitor.

^cInclusion in the ACG Guidelines does not denote endorsement of DUPIXENT by ACG.

IMPORTANCE OF DIAGNOSIS

EoE symptoms could worsen from inflammatory to fibrostenotic over time. With every year of symptoms before an EoE diagnosis, there is an 8% increased risk of fibrostenosis. Additionally, the risk of stricture development increases significantly over time. Working with a specialist at an early stage can facilitate a timely diagnosis and effective EoE management, reducing the risk of complications.^5,6,7

Diagnosis requires an endoscopy and a biopsy, which are performed by a gastroenterologist (GI).⁴

HOW TO RECOGNIZE EoE
IN PATIENTS

Signs and symptoms more frequently
seen in adolescents and adults
(≥12 years)^3,4,8:

Dysphagia

Food
impaction

Painful
swallowing

Signs and symptoms more frequently
seen in infants and children
(1-11 years)^9,10:

Stomach pain

Heartburn

Acid reflux

Regurgitation

Vomiting

Difficulty swallowing

Food getting
stuck

Food refusal

Since EoE shares similar symptoms with gastroesophageal reflux disease (GERD) and other atopic conditions, misdiagnosis is common. As recommended by the American Society for Gastrointestinal Endoscopy (ASGE), ensuring your patient gets an endoscopy is critical to avoid unnecessary delays in their diagnosis and treatment.^6,11,12

Hear from a provider:
Dr. Wechsler, MD, MSCI

Listen to Dr. Wechsler on the importance of understanding the 
different presentations of EoE.

Dr. Wechsler, MD, MSCI

One of the challenges I find with patients, actually, and especially taking care of kids is really understanding what’s actually going on with them. And we talked about before the idea of Talk Back, the idea that I hear something and I repeat it back, and I actually do that a lot with symptoms because I think it can be very challenging to communicate what’s going on with you or make sure that there’s a clear understanding of the disease.

DUPIXENT MyWay is a patient support program that can help enable access to DUPIXENT and offers financial assistance for eligible patients, one-on-one nursing support, and more.

ACG, American College of Gastroenterology.

Discover DUPIXENT MyWay Program benefits

DUPIXENT MyWay ENROLLMENT FORMS
English Enrollment Form
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See how we can do more than fine, with results across histology, symptoms, and endoscopic features