)
DOSING FOR PATIENTS WITH AFRS1
Adult
(aged 18+ years)
Every2 Weeks
1 pre-filled pen or syringea
Pediatric
(aged 6-17 years)
Every4 Weeks
1 pre-filled pen or syringea
Every2 Weeks
1 pre-filled pen or syringea
Every2 Weeks
1 pre-filled pen or syringea
Consider Before Injecting1
DUPIXENT is administered by subcutaneous injection and is intended for use under the guidance of a healthcare provider.
- Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use, according to the Instructions for Use
- Rotate injection site with each injection
- A caregiver or patient may inject DUPIXENT after training in subcutaneous injection technique using the pre-filled syringe or pre-filled pen
- Consider completing all age-appropriate vaccinations as recommended by current immunization guidelines prior to initiating treatment with DUPIXENT
Two Administration Options for You and Your Patients1-5
Important Administration Instructions1
- Patients and/or caregivers should read the Instructions for Use prior to injecting
- Instruct patients and/or caregivers to administer the subcutaneous injection
into the thigh or abdomen, except for the 2 inches (5 cm) around the navel - The upper arm can also be used if a caregiver administers the injection
- It is important to rotate the injection site with each injection. DO NOT inject
DUPIXENT into skin that is tender, damaged, bruised, or scarred
See the Instructions for Use for more detailed instructions on the preparation and administration of DUPIXENT.
Pre-filled Pen
For additional administration information, see Prescribing Information here.
Missed dose information1
If an every-2-week dose is missed, administer the injection within 7 days from the missed dose and then resume the patient’s original schedule. If the missed dose is not administered within 7 days, administer the dose, starting a new schedule based on this date.
If an every-4-week dose is missed, administer the injection within 7 days from the missed dose and then resume the patient’s original schedule. If the missed dose is not administered within 7 days, administer the dose, starting a new schedule based on this date.
Before injection, instruct patients and/or caregivers to remove DUPIXENT from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.
- 45 minutes for the 300 mg/2 mL
pre‑filled syringe or pre-filled pen - 30 minutes for the 200 mg/1.14 mL
pre-filled syringe or pre-filled pen
Patients and/or caregivers should inspect DUPIXENT visually for particulate matter and discoloration prior to administration.
- Do not use if the liquid contains visible particulate matter or is discolored or cloudy (other than clear to slightly opalescent, colorless to pale yellow)
Patients and/or caregivers should discard any unused product remaining in the pre‑filled syringe or pre-filled pen in accordance with local requirements.
- DUPIXENT is sterile and preservative‑free. Patients and/or caregivers should discard any unused portion
- Patients and/or caregivers should store DUPIXENT by refrigerating at 36 °F to 46 °F (2 °C to 8 °C) in the original carton to protect from light
- If necessary, DUPIXENT may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. DUPIXENT should not be stored above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded
- DUPIXENT should not be exposed to heat or direct sunlight
- Any unused medicinal product or waste material should be disposed of in accordance with local requirements
- DO NOT freeze. DO NOT shake
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