Skip to main content
Sense of Smell

PATIENTS EXPERIENCED RAPID
IMPROVEMENT IN SENSE
OF SMELL WITH
DUPIXENT AS EARLY AS WEEK 2a

Not an actual DUPIXENT patient.

PATIENTS EXPERIENCED RAPID
IMPROVEMENT IN SENSE
OF SMELL WITH
DUPIXENT AS EARLY AS WEEK 2a

Not an actual DUPIXENT patient.

IMPROVEMENT WITH DUPIXENT VS PLACEBO IN OLFACTORY FUNCTION
(UPSIT SCORE) AT WEEK 24, SUSTAINED THROUGH WEEK 521

aImprovement in mean UPSIT score in the DUPIXENT group was observed as early as the first assessment at Week 2, UPSIT score increase of 6.03 from a baseline score of 15.75 with DUPIXENT (n=33) vs increase of 0.17 from a baseline score of 17.19 with placebo (n=29); LSM difference vs placebo: 5.86 (95% CI: 2.32, 9.39).1

bAt Week 24 (secondary endpoint), UPSIT score increase of 8.87 from a baseline score of 15.75 with DUPIXENT (n=33) vs increase of 4.41 from a baseline score of 17.19 with placebo (n=29); LSM difference between DUPIXENT and placebo: 4.46 (95% CI: 0.22, 8.71) (P=0.0392).1

cAt Week 52, UPSIT score increase of 9.45 from a baseline score of 15.75 with DUPIXENT (n=33) vs increase of 2.12 from a baseline score of 17.19 with placebo (n=29); LSM difference between DUPIXENT and placebo: 7.33 (95% CI: 3.06, 11.59).1

University of Pennsylvania Smell Identification Test (UPSIT) score: Patients respond to a 40-odorant test to assess olfactory function. The maximum score is 40, with ≤18 indicating anosmia. Higher score indicates improvement (better olfaction).1

LSM, least squares mean.

Explore DUPIXENT
Results in Surgery/
Steroid Use
and
Serum IgE

SURGERY AND STEROID USE SERUM IgE Study design and safety data