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DOSAGE AND ADMINISTRATION

YOU DECIDE: PATIENTS SELF-ADMINISTER AT HOME OR YOU ADMINISTER IN THE OFFICE1

Not actual
DUPIXENT patients.

Not actual
DUPIXENT patients.

No loading dose required1

1 pre-filled pen or syringea

a300 mg=2 mL solution.1

FLEXIBLE AT-HOME OR IN-OFFICE ADMINISTRATION2,3

Considerations before injecting

DUPIXENT is an injectable medicine that is administered subcutaneously and is intended for use under the guidance of a healthcare provider.1

  • A caregiver or patient 18 years of age and older may inject DUPIXENT after training in subcutaneous injection technique using the pre-filled
    syringe or pre-filled pen
  • Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use, according to the
    Instructions for Use
  • Consider completing all age-appropriate vaccinations as recommended by current immunization guidelines prior to initiating treatment with
    DUPIXENT

Important administration
instructions1

  • Administer the subcutaneous injection into the thigh or abdomen, except for the 2
    inches (5 cm) around the navel, or outer upper arms (caregiver only)
  • Rotate the injection site with each injection
  • DO NOT inject DUPIXENT into skin that is tender, damaged, bruised, or scarred

If a dose is missed1:

  • If a dose is missed, instruct the patient to administer the injection within 7 days from the missed dose and then resume the original schedule. If the missed dose is not administered within 7 days, instruct the patient to wait until the next dose on the original schedule (for an every‑other‑week dose) or administer the dose, starting a new schedule based on this date (for an every‑4‑week dose).1
  • For additional details, please see Important Safety Information, full Prescribing Information, and Instructions for Use

Preparation for use1

Before injection, instruct patients and/or caregivers to remove DUPIXENT from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.

  • 45 minutes for the 300 mg/2 mL pre‑filled syringe or pre-filled pen
  • Patients and/or caregivers should inspect DUPIXENT visually for
    particulate matter and discoloration prior to administration
  • Do not use if the liquid contains visible particulate matter or is
    discolored or cloudy (other than clear to slightly opalescent, colorless
    to pale yellow)
  • Patients and/or caregivers should discard any unused product
    remaining in the pre‑filled syringe or pre-filled pen in accordance with
    local requirements

Storage and handling1

  • DUPIXENT is sterile and preservative-free. Discard any unused portion
  • Store refrigerated at 36 °F to 46 °F (2 °C to 8 °C) in the original carton to protect from light
  • If necessary, DUPIXENT may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. DUPIXENT should not be stored above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded
  • Do not expose DUPIXENT to heat or direct sunlight
  • Any unused medicinal product or waste material should be disposed of in accordance with local requirements
  • Do NOT freeze. Do NOT shake

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