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DOSAGE AND ADMINISTRATION

YOU DECIDE: PATIENTS SELF-ADMINISTER AT HOME OR YOU ADMINISTER IN THE OFFICE1

Not actual
DUPIXENT patients.

Not actual
DUPIXENT patients.

No loading dose required1

1 pre-filled pen or syringea

a300 mg=2 mL solution.1

FLEXIBLE AT-HOME OR IN-OFFICE ADMINISTRATION2,3

Considerations before injecting

DUPIXENT is an injectable medicine that is administered subcutaneously and is intended for use under the guidance of a healthcare provider.1

  • DUPIXENT is administered by subcutaneous injection and is intended for use under the guidance of a healthcare provider
  • A caregiver or patient 18 years of age and older may inject DUPIXENT after training in subcutaneous injection technique using the pre-filled
    syringe or pre-filled pen
  • Provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use, according to the
    Instructions for Use
  • Consider completing all age-appropriate vaccinations as recommended by current immunization guidelines prior to initiating treatment with
    DUPIXENT

Important administration
instructions1

  • Administer the subcutaneous injection into the thigh or abdomen, except for the 2
    inches (5 cm) around the navel, or outer upper arms (caregiver only)
  • Rotate the injection site with each injection
  • DO NOT inject DUPIXENT into skin that is tender, damaged, bruised, or scarred

If a dose is missed1:

  • If a dose is missed, instruct the patient to administer the injection within 7 days from the missed dose and then resume the original schedule. If the missed dose is not administered within 7 days, instruct the patient to wait until the next dose on the original schedule (for an every‑other‑week dose) or administer the dose, starting a new schedule based on this date (for an every‑4‑week dose).1
  • For additional details, please see Important Safety Information, full Prescribing Information, and Instructions for Use

Preparation for use1

Before injection, instruct patients and/or caregivers to remove DUPIXENT from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.

  • 45 minutes for the 300 mg/2 mL pre‑filled syringe or pre-filled pen
  • Patients and/or caregivers should inspect DUPIXENT visually for
    particulate matter and discoloration prior to administration
  • Do not use if the liquid contains visible particulate matter or is
    discolored or cloudy (other than clear to slightly opalescent, colorless
    to pale yellow)
  • Patients and/or caregivers should discard any unused product
    remaining in the pre‑filled syringe or pre-filled pen in accordance with
    local requirements

Storage and handling1

  • DUPIXENT is sterile and preservative-free. Discard any unused portion
  • Store refrigerated at 36 °F to 46 °F (2 °C to 8 °C) in the original carton to protect from light
  • If necessary, DUPIXENT may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. DUPIXENT should not
    be stored above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded
  • Do not expose DUPIXENT to heat or direct sunlight
  • Any unused medicinal product or waste material should be disposed of in accordance with local requirements
  • Do NOT freeze. Do NOT shake

COPD, chronic obstructive pulmonary disease.

FREQUENTLY ASKED QUESTIONS

The recommended dosage of DUPIXENT for adult patients is 300 mga given every other week (Q2W). No loading dose is required.1

a300 mg=2 mL solution.

COPD, chronic obstructive pulmonary disease.