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REDUCTION IN ITCH AND HIVES
IN BIOLOGIC-NAIVEa PATIENTS1,2

Iss7

Reduction in weekly itch
severity score at Week 24

EXPLORE ITCH EFFICACY

Hss7

Reduction in weekly hives
severity score at Week 24

EXAMINE HIVES EFFICACY

UAS7 (ISS7+HSS7)

Reduction in disease activity at
Week 24, with some patients even
reporting complete response

EVALUATE OUTCOMES
  • aBiologic-naive defined as no anti-IgE treatment.

Demonstrated safety profile in csu1

Most common adverse reactions
(incidence ≥2%) in patients with
chronic spontaneous urticaria are
injection site reactions.b

  • bInjection site reactions cluster includes injection site dermatitis, injection site erythema, injection site hematoma, injection site induration, injection site pain, injection site pruritus, injection site reaction, injection site swelling.

Explore safety profile

Safety profile studied in >8900 patients across
us-approved indications1,c

  • cPatient total included patients in AD trials (SOLO 1, SOLO 2, CHRONOS, AD-1021, AD-1526, AD-1652, AD-1539, and AD-HAFT), asthma trials (DRI12544, QUEST, VENTURE,
    and VOYAGE), CRSwNP trials (SINUS-24 and SINUS-52), EoE trials (EoE-1 and EoE-2), PN trials (PRIME and PRIME2), COPD trials (BOREAS and NOTUS), and CSU trials
    (CUPID-A, CUPID-B, and CUPID-C).

the only dual inhibitor of il-4
and il-13 signaling

The mechanism of dupilumab action
has not been definitively established.

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DUPIXENT Attributes And Considerations

NOT AN
IMMUNOSUPPRESSANT
OR
A STEROID1

NO INITIAL LAB TESTING
OR
ONGOING LAB
MONITORING

according to the
Prescribing Information1

NO KNOWN DRUG‑TO‑DRUG
INTERACTIONS1

  • Not metabolized through
    the liver or
    excreted
    through the kidneys

At-home
self-
administration1

  • Train patients and/or
    caregivers on
    proper
    administration prior to use

NO boxed warning1

Please see additional
Warnings and Precautions
in the Prescribing
Information and Important
Safety Information below.

Select important safety information

WARNINGS AND PRECAUTIONS

  • Hypersensitivity: Hypersensitivity reactions, including anaphylaxis, acute generalized exanthematous pustulosis (AGEP), serum sickness or serum
    sickness-like reactions, angioedema, generalized urticaria, rash, erythema nodosum, and erythema multiforme have been reported. A case of AGEP
    was reported in an adult subject who participated in the bullous pemphigoid development program. If a clinically significant hypersensitivity reaction
    occurs, institute appropriate therapy and discontinue DUPIXENT.

More than 1 million patients

On Therapy Across
Approved
indications
Worldwide2,d

  • dThis worldwide number is largely comprised from 10 countries (Canada, China, France, Germany, Italy, Japan, the Netherlands, Spain, the UK, and the US), with the rest of the world comprising ≈10% of this number. This number is comprised of the following US approved indications: AD, asthma, COPD, CRSwNP, PN, and EoE. Data through February 2025.
  • AD, atopic dermatitis; COPD, chronic obstructive pulmonary disease; CRSwNP, chronic rhinosinusitis with nasal polyps; EoE, eosinophilic esophagitis; HSS7, hives severity score over 7 days; ISS7, itch severity score over 7 days; PN, prurigo nodularis; UAS7, urticaria activity score over 7 days.

Discover who may be appropriate for DUPIXENT

See profiles of potential CSU patients you might see in your practice.

Identify Patients
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DUPIXENT MyWay is a patient support program that can help enable access to DUPIXENT and offers financial assistance for eligible patients, one-on-one nursing support, and more.

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DUPIXENT MyWay
ENROLLMENT FORMS
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