Significantly Reduced the Need for SCS Use or Sino‑Nasal Surgery vs Placebo in a Prespecified Multiplicity‑Controlled Pooled Analysis of SINUS‑24 and SINUS‑521,2,a

TIME TO FIRST SCS USE OR CRSwNP SURGERY DURING THE TREATMENT PERIOD

74%
Fewer Patients Required
SCS Use at Week 52
(HR: 0.26 [95% CI: 0.18, 0.38])1
  • 75% REDUCTION IN SCS COURSES PER YEAR
    (RR: 0.25 [95% CI: 0.17, 0.37])1

83%
Fewer Patients Required sino-nasal
surgery at week 52
(HR: 0.17 [95% CI: 0.07, 0.46])1

aIndividually, SCS reduction and need for sino-nasal surgery were not multiplicity-adjusted endpoints.3

HR, hazard ratio; RR, risk ratio.