Learn About Patient Types Who Are Right for DUPIXENT

DUPIXENT is approved for use in appropriate CRSwNP patients with or without prior sino-nasal surgery

Examples of patients with a history of asthma, previous sino-nasal surgery, or comorbid NSAID-ERD:

 

CRSwNP Patient With
History of Asthma

Medical History

  • Confirmed diagnosis of CRSwNP by visual examination
  • CRSwNP duration: 8 years
  • 2 SCS bursts in the previous year
  • INCS
  • History of asthma
  • No previous sino-nasal surgery

Clinical Characteristics

Nasal Congestion (NC) Score (0-3): 2

Nasal Polyp Score (NPS)
(0-8): 6

SNOT-22 Score (0-110): 46

48 years old

Patient profile is representative and is not an actual DUPIXENT patient.

CRSwNP Patient With
Previous Sino-Nasal
Surgery

Medical History

  • Confirmed diagnosis of CRSwNP by rhinoscopy (endoscopy)
  • CRSwNP duration: 12 years
  • 1 previous sino-nasal surgery
  • 3 SCS bursts in the previous year
  • Nasal irrigation and INCS for nasal symptoms
  • Reports loss of smell and congestion

Clinical Characteristics

Nasal Congestion (NC) Score (0-3): 3

Nasal Polyp Score (NPS)
(0-8): 6

SNOT-22 Score (0-110): 55

51 years old

Patient profile is representative and is not an actual DUPIXENT patient.

CRSwNP Patient With
Comorbid NSAID-ERD

Medical History

  • Confirmed diagnosis of comorbidities:
    • CRSwNP by anterior rhinoscopy and endoscopy 14 years ago
    • Asthma 10 years ago
    • NSAID-ERD by aspirin challenge
  • 2 OCS bursts in the past year
  • 3 previous sino-nasal surgeries
  • Reports loss of smell
  • INCS and medium-dose ICS/LABA

Clinical Characteristics

Bilateral Endoscopic Nasal Polyp Score (NPS) (0-8): 6

LMK-CT Score (0-24): 18

SNOT-22 Score (0-110): 55

FEV1: 60% of predicted

45 years old

Patient profile is representative and is not an actual DUPIXENT patient.

FEV1, forced expiratory volume in 1 second; ICS, inhaled corticosteroid; LABA, long-acting beta agonist; LMK-CT, Lund-Mackay computed tomography;
NC, nasal congestion/obstruction; NPS, nasal polyp score; NSAID-ERD, nonsteroidal anti-inflammatory drug-exacerbated respiratory disease; OCS,
oral corticosteroid; SNOT-22, 22-item Sino-Nasal Outcome Test.


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