Skip to main content

DOSAGE AND ADMINISTRATION

YOU DECIDE: PATIENTS SELF-ADMINISTER AT
HOME OR YOU ADMINISTER IN THE OFFICE1

YOU DECIDE: PATIENTS SELF-ADMINISTER AT
HOME OR YOU ADMINISTER IN THE OFFICE1

DOSAGE FOR ADULTS AND ADOLESCENTS (12+ YEARS)1

Adults and adolescents (12+ years) with inadequately controlled CRSwNP1

12+ YEARS

No loading dose

300 mg once every
two weeksa

1 pre-filled pen or syringe

a300 mg=2 mL solution.1

For supplemental injection training, visit our Patient Video Injection Support page.

Two Administration Options for You and Your Patients1-3

Consider Before Injecting1

DUPIXENT is a medicine that is administered by subcutaneous injection and is intended for use under the guidance of a
healthcare provider.1

  • In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under the supervision of an adult
  • A patient may self-inject DUPIXENT—or a caregiver may administer DUPIXENT—after training has been provided by a healthcare
    provider on proper subcutaneous injection technique using the pre-filled syringe or pre-filled pen
  • It is important to provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use
  • Advise patients to follow sharps disposal recommendations after administration

Important Administration Instructions1

  • Patients and/or caregivers should read the Instructions for Use prior to injecting
  • Instruct patients and/or caregivers to administer the subcutaneous injection
    into the thigh or abdomen, except for the 2 inches (5 cm) around the navel
  • The upper arm can also be used if a caregiver administers the injection
  • It is important to rotate the injection site with each injection. DO NOT inject
    DUPIXENT into skin that is tender, damaged, bruised, or scarred
  • If a dose is missed, instruct the patient to administer the injection within
    7 days from the missed dose and then resume their original schedule. If the
    missed dose is not administered within 7 days, instruct the patient to wait
    until the next dose on the original schedule

Additional Dosing Information

Before injection, instruct patients and/or caregivers to remove DUPIXENT from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.

  • 45 minutes for the 300 mg/2 mL pre‑filled syringe or pen

Patients and/or caregivers should inspect DUPIXENT for particulate matter and discoloration prior to administration.

  • Do not use if the liquid contains visible particulate matter or is discolored or cloudy (other than clear to slightly opalescent, colorless to pale yellow)

Patients and/or caregivers should discard any unused product remaining in the pre‑filled syringe or pen in accordance with local requirements.