One subcutaneous injection every 2 weeks after an initial loading dose1
Train patients and/or caregivers on proper administration prior to use
- In adults with bullous pemphigoid, use DUPIXENT in combination with a tapering course of oral corticosteroids
- Once disease control has occurred, gradually taper corticosteroids, after which continue DUPIXENT as monotherapy
- In case of relapse, corticosteroids may be added if medically advisable
18+ years
One dosage regimen, regardless of weight
INITIAL LOADING DOSE
600 mg
(2 x 300 mg)
FOLLOWED BY
300 mg Q2W
(1 x 300 mg)
Get the full dosing regimen
For supplemental injection training, visit our Patient Video Injection Support page
No reconstitution needed
Available in a 300 mg pre-filled pen or pre-filled syringe for subcutaneous injection1
At-home or in-office administration options1,2
Consider before injecting1
- DUPIXENT is an injectable medicine that is administered by subcutaneous injection and is intended for use under the guidance of a healthcare provider
- A patient may self-inject DUPIXENT—or a caregiver may administer DUPIXENT—after training has been provided by a healthcare provider on proper subcutaneous injection technique using the pre-filled syringe or pre-filled pen
- It is important to provide proper training to patients and/or caregivers on the preparation and administration of DUPIXENT prior to use, according to the Instructions for Use
- After administration, advise patients to follow sharps disposal recommendations
- Patients and/or caregivers should read all the Instructions for Use—300 mg pre-filled pen or pre-filled syringe—prior to injecting
- Consider completing all age-appropriate vaccinations as recommended by current immunization guidelines prior to initiating treatment with DUPIXENT
Important administration
instructions1,2
Preparation and administration of DUPIXENT
- Patients and/or caregivers should read the Instructions for Use prior to injecting
- Instruct patients and/or caregivers to administer the subcutaneous
injection into the thigh or abdomen, except for the 2 inches (5 cm)
around the navel - The upper arm can also be used if a caregiver administers the injection
- It is important to rotate the injection site with each injection. DO NOT inject DUPIXENT into skin that is tender, damaged, bruised, or scarred
- For the initial dose, patients and/or caregivers should administer each DUPIXENT injection at a different injection site
See the Instructions for Use for more detailed instructions on the preparation and administration of DUPIXENT.
For supplemental injection training, visit our
Patient Video Injection Support page
Outer Upper Arms
Abdomen
Thighs
Injection by caregiver only
Self-injection or by caregiver
Pre-filled Syringe
Pre-filled Pen
Additional dosage information
Before injection, instruct patients and/or caregivers to remove the DUPIXENT pre‑filled pen or syringe from the refrigerator and allow DUPIXENT to reach room temperature without removing the needle cap.
- 45 minutes for the 300 mg/2 mL pre-filled pen or syringe
Patients and/or caregivers should not use the pre-filled pen or syringe if the liquid contains visible particulate matter, or is discolored or cloudy (other than clear to slightly opalescent, colorless to pale yellow).
Patients and/or caregivers should discard any unused product remaining in the pre-filled pen or syringe in accordance with local requirements.
For supplemental injection training, visit our Patient Video Injection Support Page
DUPIXENT is a clear to slightly opalescent, colorless to pale yellow solution available as:
- Injection: 300 mg/2 mL in a single-dose, pre-filled pen with hidden needle or syringe with needle shield
DUPIXENT is available in cartons containing 2 pre-filled pens or syringes with needle shields. Each 300 mg pre-filled syringe or pre-filled pen delivers 300 mg/2 mL.
- DUPIXENT is sterile and preservative-free. Patients and/or caregivers should discard any unused portion
- Patients and/or caregivers should store DUPIXENT by refrigerating between 36 °F to 46 °F (2 °C to 8 °C) in the original carton to protect from light
- If necessary, pre-filled pens or syringes may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. DUPIXENT should not be stored above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded
- Do not expose DUPIXENT to heat or direct sunlight
- Do NOT freeze. Do NOT shake
- Any unused medicinal product or waste material should be disposed of in accordance with local requirements
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Q2W, once every 2 weeks.