Has DUPIXENT been shown to provide significant nodule clearance in prurigo nodularis?

DUPIXENT patients achieved significant nodule clearance at Week 24 in PRIME and PRIME2, two phase 3, placebo-controlled, pivotal trials.^1,3

In PRIME, 48% achieved clear or almost-clear skin (≤5 nodules) vs 18% with placebo (P<0.001, secondary endpoint)
In PRIME2, 45% achieved clear or almost-clear skin (≤5 nodules) vs 16% with placebo (P<0.001, secondary endpoint)

See real-world nodule clearance data