What is the dosage regimen of DUPIXENT in patients with CSU?

&ge;60 kg: 600 mg loading dose (2 x 300 mg SC injections), then 300 mg (1 SC injection)&nbsp;every two weeks
30 kg to &lt;60 kg: 400 mg loading dose (2 x 200 mg SC injections), then 200 mg (1 SC injection) every&nbsp;two weeks
15 kg to &lt;30 kg: 600 mg loading dose (2 x 300 mg SC injections), then 300 mg (1 SC injection) every 4 weeks

DUPIXENT has one dosing regimen in adults and weight-tiered dosing in pediatric populations (ages 2 to 17 years).¹

One dosage regimen in adults regardless of weight

600 mg loading dose (2 x 300 mg SC injections), then 300 mg (1 SC injection) every two weeks

Weight-tiered dosing in pediatric patients 6 to 17 years of age

≥60 kg: 600 mg loading dose (2 x 300 mg SC injections), then 300 mg (1 SC injection) every two weeks
30 kg to <60 kg: 400 mg loading dose (2 x 200 mg SC injections), then 200 mg (1 SC injection) every two weeks
15 kg to <30 kg: 600 mg loading dose (2 x 300 mg SC injections), then 300 mg (1 SC injection) every 4 weeks

Weight-tiered dosing in pediatric patients 2 to 5 years of age

15 kg to <30 kg: 300 mg (1 SC injection) every 4 weeks (no initial loading dose is recommended)
5 kg to <15 kg: 200 mg (1 SC injection) every 4 weeks (no initial loading dose is recommended)