The dosing for adolescents, children, and infants to preschoolers is weight tiered. For your adolescent patients (12 to 17 years of age) who weigh ≥60 kg (132 lb), the dosing will be the same as patients aged 18 years and older. Specifically, a loading dose of 600 mg (2 x 300 mg subcutaneous [SC] injections in different injection sites) followed by 300 mg (1 SC injection) given every other week.1
For your pediatric patients (6 to 17 years of age) who weigh 30 kg (66 lb) to less than 60 kg (132 lb), the recommended dose is a loading dose of 400 mg (2 x 200 mg SC injections in different injection sites) followed by 200 mg (1 SC injection) given every other week. For patients who weigh 15 kg (33 lb) to less than 30 kg (66 lb), the recommended dose is a loading dose of 600 mg (2 x 300 mg SC injections in different injection sites) followed by 300 mg (1 SC injection) given every 4 weeks.1
For your pediatric patients (6 months to 5 years) who weigh 15 kg (33 lb) to less than 30 kg (66 lb), the recommended dose is 300 mg (1 SC injection) given every 4 weeks. For patients who weigh 5 kg (11 lb) to less than 15 kg (33 lb), the recommended dose is 200 mg (1 SC injection) given every 4 weeks. No initial loading dose is recommended for patients aged 6 months to 5 years.1
DUPIXENT can be used with or without TCS.1