It takes 2 weeks for DUPIXENT to take effect as seen by the rapid breathing relief in lung function as early as Week 2. Approximately 72% of the total FEV₁ improvement (470 mL improvement at Week 52 from baseline FEV1 of 1.78 L) was seen at Week 2 in patients taking DUPIXENT 200 mg Q2W + SOC (n=264) (baseline blood EOS ≥300 cells/μL, QUEST, secondary endpoint).^1,7,8