WEEK 16
EoE KIDS-Part A
Secondary Endpoint
EoE KIDS-Part A
Secondary Endpoint
WEEK 52
EoE KIDS-Part B
Secondary Endpoint
EoE KIDS-Part B
Secondary Endpoint
CHANGES IN ENDOSCOPIC FEATURES WERE OBSERVED
Improvements in EREFS total scores were observed
at Weeks 16 and 52 with DUPIXENT1,2
Reduction in EREFS
total scorea
Thresholds for clinically meaningful changes in EREFS scores have not been established. Results are descriptive in the extended active treatment period at Week 52. Definitive conclusions cannot be made due to limitations associated with extended active treatment design, including lack of comparator arm and decreasing sample size.
aReductions indicate improvements in score.
Endoscopic
Reference Score
(EREFS)3
EREFS is a clinician-reported rating of the severity of 5 endoscopic features:
edema, rings, exudates, furrows, and stricture.