/*!
 * Bootstrap v3.3.7 (http://getbootstrap.com)
 * Copyright 2011-2016 Twitter, Inc.
 * Licensed under MIT (https://github.com/twbs/bootstrap/blob/master/LICENSE)
 */
.hero-title {
    background: #018c5e;
    color: white;
    display: flex;
    flex-direction: column;
    justify-content: center;
    height: 87px
}

.hero-title h1 {
    margin: 0;
    padding: 0;
    line-height: 1;
    font-size: 24px
}

@media(max-width:991px) {
    .hero-title h1 {
        text-align: center
    }
}

.inner-hero {
    background: #096;
    background: linear-gradient(90deg, #096 0, #096 75%, #88c354 100%);
    position: relative
}

.inner-hero:before {
    content: "";
    position: absolute;
    bottom: 0;
    display: block;
    width: 100%;
    height: 100px;
    background: linear-gradient(185deg, rgba(19, 154, 104, 0) 0, transparent 60%, rgba(0, 0, 0, 0.2) 100%)
}

.inner-hero .score-inner .hero-left {
    color: white
}

@media(min-width:992px) {
    .inner-hero .score-inner .hero-left {
        height: 375px;
        display: flex;
        flex-direction: column;
        justify-content: center
    }
}

.inner-hero .score-inner .hero-left h2,
.inner-hero .score-inner .hero-left .h2 {
    font-weight: 500;
    color: white
}

@media(max-width:991px) {

    .inner-hero .score-inner .hero-left h2,
    .inner-hero .score-inner .hero-left .h2 {
        text-align: center;
        margin: 35px 0 25px
    }
}

@media(max-width:991px) {
    .inner-hero .score-inner .hero-left p {
        text-align: center
    }
}

@media(max-width:991px) {
    .inner-hero .score-inner .hero-left p.footnotes {
        text-align: left
    }
}

.inner-hero .score-inner .hero-right {
    background: white;
    border-top: 14px solid #91c500;
    text-align: center;
    box-shadow: 0 40px 40px rgba(0, 0, 0, 0.5);
    display: flex;
    flex-direction: column;
    justify-content: center
}

@media(min-width:1200px) {
    .inner-hero .score-inner .hero-right {
        width: 445px
    }
}

@media(min-width:992px) {
    .inner-hero .score-inner .hero-right {
        height: 420px;
        top: -38px;
        position: absolute;
        right: 15px
    }
}

@media(max-width:991px) {
    .inner-hero .score-inner .hero-right {
        margin-right: 15px;
        margin-left: 15px;
        padding: 30px
    }
}

.inner-hero .score-inner .hero-right:before {
    content: "";
    position: absolute;
    bottom: 0;
    left: 0;
    margin: 0 -15px;
    display: block;
    width: 100%;
    height: 100px;
    background: linear-gradient(185deg, rgba(19, 154, 104, 0) 0, transparent 60%, rgba(0, 0, 0, 0.05) 100%)
}

.inner-hero .score-inner .hero-right img {
    width: 136px;
    height: auto;
    margin: 0 auto 24px
}

@media(max-width:767px) {
    .inner-hero .score-inner .hero-right img {
        width: 100px
    }
}

.inner-hero .score-inner .hero-right p {
    font-size: 22px;
    line-height: 1.35
}

@media(max-width:991px) {
    .mechanism-of-action .hero-right img {
        margin-bottom: 12px !important
    }

    .dosing-and-administration .inner-hero:before {
        background: -webkit-linear-gradient(90deg, rgba(225, 225, 225, 0.1) 100%, transparent 57%, rgba(0, 0, 0, 0.02) 50%, rgba(0, 0, 0, 0.03) 50%);
        height: 55%
    }
}

div[class*=' section']:not(.section-references) .container {
    padding: 50px 0 30px
}

@media(max-width:991px) {
    div[class*=' section']:not(.section-references) .container {
        padding: 0 15px
    }
}

@media(max-width:767px) {
    div[class*=' section']:not(.section-references) .container {
        padding: 25px 15px 0
    }
}

.adult-table {
    margin: 50px 0
}

@media(max-width:991px) {
    .adult-table {
        margin: 30px 0
    }
}

.adult-table .adult-table-title {
    color: #096;
    padding: 5px 20px
}

.adult-table .adult-table-title h5 {
    text-transform: initial
}

.adult-table .adult-table-body {
    display: flex;
    margin: 5px 0 0 0
}

@media(max-width:991px) {
    .adult-table .adult-table-body {
        margin: -5px 0 0 0;
        flex-direction: column
    }
}

.adult-table .adult-table-body .adult-table-body-part {
    border-right: 5px solid white;
    width: 70%
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part {
        border-right: 0;
        width: 100%;
        display: flex;
        flex-direction: row;
        margin: 10px 0 0 0
    }
}

.adult-table .adult-table-body .adult-table-body-part .head {
    background: #096;
    color: white;
    min-height: 160px;
    text-align: center;
    margin: 0 0 5px;
    font-size: 16px;
    line-height: 1;
    padding: 10px;
    display: flex;
    align-items: center;
    justify-content: center
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .head {
        width: 50%;
        min-height: auto;
        padding: 20px 10px;
        margin: 0;
        text-align: left;
        justify-content: left
    }
}

.adult-table .adult-table-body .adult-table-body-part .body {
    background: #e5e4e4;
    text-align: center;
    padding: 10px;
    min-height: 260px;
    display: flex;
    align-items: center;
    justify-content: center
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .body {
        width: 50%;
        min-height: auto;
        padding: 20px 10px
    }
}

.adult-table .adult-table-body .adult-table-body-part .body-inner {
    display: flex;
    text-align: center;
    justify-content: space-evenly;
    width: 100%
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .body-inner {
        flex-direction: column;
        text-align: left
    }
}

.adult-table .adult-table-body .adult-table-body-part .body-inner>div {
    width: 100%;
    display: flex;
    flex-direction: column;
    justify-content: center
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .body-inner>div {
        width: 100%;
        margin: 0 0 20px
    }
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .body-inner>div:last-child {
        margin: 0
    }
}

.adult-table .adult-table-body .adult-table-body-part p {
    margin-bottom: 0
}

.adult-table .adult-table-body .adult-table-body-part .part-title {
    margin: 0 0 30px
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .part-title {
        position: absolute;
        top: 0;
        background: #096;
        left: 0;
        right: 0;
        width: 100%;
        margin: 0 auto;
        padding: 20px 10px;
        z-index: 1;
        border-bottom: 2px solid white;
        text-align: left
    }
}

.adult-table .adult-table-body .adult-table-body-part .font-26 {
    font-size: 26px
}

.adult-table .adult-table-body .adult-table-body-part small {
    font-size: 65%;
    position: relative;
    top: -7%
}

.adult-table .adult-table-body .adult-table-body-part span {
    font-size: 17px;
    line-height: 1
}

.adult-table .adult-table-body .adult-table-body-part .b-right {
    position: relative
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part .b-right::after {
        content: " ";
        position: absolute;
        border-bottom: 2px solid white;
        top: 15px;
        right: 0;
        width: 100%;
        height: 100%
    }
}

.adult-table .adult-table-body .adult-table-body-part.data-divider {
    width: 100%
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part.data-divider {
        position: relative;
        padding: 60px 0 0 0
    }
}

.adult-table .adult-table-body .adult-table-body-part.data-divider .head {
    flex-direction: column
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part.data-divider .head {
        justify-content: center
    }
}

.adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner {
    position: relative
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner {
        text-align: left
    }
}

.adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner:after {
    content: " ";
    position: absolute;
    width: 2px;
    height: 100%;
    background: white;
    left: 48%
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner:after {
        display: none
    }
}

.adult-table .adult-table-body .adult-table-body-part.data-divider .body {
    position: relative
}

.adult-table .adult-table-body .adult-table-body-part.data-divider .body:after {
    content: " ";
    position: absolute;
    width: 2px;
    height: 80%;
    left: 48%;
    background: white
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part.data-divider .body:after {
        display: none
    }
}

.adult-table .adult-table-body .adult-table-body-part:last-child {
    border-right: 0
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part:last-child {
        position: relative;
        padding: 60px 0 0 0
    }
}

.adult-table .adult-table-body .adult-table-body-part:last-child .head {
    display: flex;
    flex-direction: column
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part:last-child .head {
        margin: 0;
        justify-content: center
    }
}

@media(max-width:991px) {
    .adult-table .adult-table-body .adult-table-body-part:last-child .head .body-inner {
        text-align: left
    }
}

@media(max-width:991px) and (min-width:768px) {
    .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right {
        margin: 30px 0 30px
    }
}

@media(max-width:767px) {
    .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right {
        margin: 15px 0 45px
    }
}

@media(max-width:991px) and (min-width:768px) {
    .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right::after {
        top: 20px
    }
}

@media(max-width:767px) {
    .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right::after {
        top: 35px
    }
}

@media(max-width:991px) {
    .adult-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
        padding: 25px 0 20px;
        border-bottom: 2px solid white;
        margin: 0 0 20px
    }

    .adult-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right:after {
        display: none
    }

    .adult-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .body .b-right {
        margin: 0 0 35px
    }
}

@media(min-width:992px) {
    .adolescent-study-design div.section-content .container {
        padding: 50px 0 0 !important
    }
}

.adolescent-study-design .adult-table .adult-table-body .adult-table-body-part .body {
    min-height: 340px
}

@media(max-width:991px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part .body {
        min-height: auto
    }
}

@media(max-width:991px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
        padding: 25px 0 20px;
        border-bottom: 2px solid white;
        margin: 0 0 20px
    }

    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right:after {
        display: none
    }

    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .body .b-right {
        margin: 0 0 35px
    }
}

@media(max-width:767px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
        padding: 10px 0 35px;
        margin: 0 0 20px
    }
}

@media(min-width:992px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column1 {
        width: 50%
    }
}

@media(min-width:992px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column2 {
        width: 50%
    }
}

@media(min-width:992px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column3 {
        width: 100%
    }
}

@media(min-width:992px) {
    .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column6 {
        width: 60%
    }
}

@media(min-width:992px) {
    .children-study-designs div.section-content .container {
        padding: 50px 0 0 !important
    }
}

@media(min-width:992px) {
    .children-study-designs div.section-content .container h2+p {
        margin-bottom: 30px
    }
}

@media(min-width:992px) {
    .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column3 {
        width: 100%
    }
}

@media(max-width:991px) {
    .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column4 {
        position: relative;
        padding: 60px 0 0 0
    }
}

.children-study-designs .adult-table .adult-table-body .adult-table-body-part.column4 .head {
    display: flex;
    flex-direction: column
}

.children-study-designs .adult-table .adult-table-body .adult-table-body-part.column4 .head .part-title {
    margin: 0 0 20px
}

@media(max-width:991px) {
    .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
        padding: 10px 0 35px;
        border-bottom: 2px solid white;
        margin: 0 0 20px
    }

    .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right:after {
        display: none
    }

    .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .body .b-right {
        margin: 0 0 35px
    }
}

@media(max-width:767px) {
    .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
        padding: 10px 0 35px
    }
}

.children-study-designs .adult-table .adult-table-body .adult-table-body-part .body {
    min-height: 370px
}

@media(max-width:991px) {
    .children-study-designs .adult-table .adult-table-body .adult-table-body-part .body {
        min-height: auto
    }
}

.treatment-effects {
    display: flex;
    text-align: center;
    margin: 60px 0 40px;
    justify-content: center
}

@media(max-width:991px) {
    .treatment-effects {
        flex-direction: row;
        flex-wrap: wrap;
        justify-content: space-evenly;
        margin-bottom: 10px
    }
}

.treatment-effects>div {
    margin: 0 60px 0 0
}

.treatment-effects>div p {
    margin: 15px 0 0
}

@media(max-width:991px) {
    .treatment-effects>div {
        margin: 0 10px 40px 0
    }
}

.btn.btn-lime-arrow {
    padding: 30px 0;
    font-size: 17px
}

.btn.btn-lime-arrow.pt-15 {
    padding-top: 15px
}

.btn-group .btn.btn-lime-arrow {
    padding: 0;
    margin-bottom: 25px
}

.btn-group+p {
    margin-bottom: 25px
}

@media(max-width:991px) {
    .btn-group.m-block {
        display: block
    }

    .btn-group.m-block .btn.btn-lime-arrow:after {
        margin-left: 5px
    }
}

sup.symbol.adjust {
    top: .5em;
    left: -5px
}

@media(max-width:991px) {
    sup.symbol.adjust {
        left: -11px
    }
}

sup.symbol.adjust1 {
    top: .5em;
    left: -10px
}

@media(max-width:991px) {
    sup.symbol.adjust1 {
        left: -19px
    }
}

@media(max-width:991px) {
    .m-text-center .btn.btn-lime-arrow {
        text-align: center
    }
}

.my-50p {
    margin: 50px 0
}

@media(max-width:991px) {
    .my-50p {
        margin: 0 0 15px 0
    }
}

@media(max-width:991px) {

    .adult-table .font-26,
    .adult-table-body-part .font-26 {
        text-align: center
    }

    .adult-table-body .column2 .head {
        align-items: start !important
    }

    .adult-table-body .column2 sup {
        left: 1px;
        top: 22px
    }

    .adult-table-body .column1 .head {
        align-items: start !important
    }

    .adult-table-body .column1 sup {
        left: -16px;
        top: 22px
    }

    .adult-table-body .column3 .head {
        align-items: start !important
    }

    .adult-table-body .column3 sup {
        top: 3px
    }

    .adult-table .adult-table-body .adult-table-body-part.column2 {
        margin-top: 2px
    }

    .adult-table .adult-table-body .adult-table-body-part.column3 {
        margin-top: 2px
    }

    sup.symbol.efficacy-sup {
        top: -0.3em
    }

    .adult-table-body sup.symbol.dosing-sup {
        top: -0.6em
    }
}

@media(min-width:768px) {
    .footnotes:not(:last-of-type) {
        padding-bottom: 10px
    }
}

.study-designs div.section-content .container h2,
.study-desigdiv.section-content .container .h2 {
    line-height: 1.2
}

@media(max-width:767px) {
    .pb-30-mob {
        padding-bottom: 30px
    }
}