/* -------------------
BEGIN core-bootstrap-variables-mixins 
Sitecore Resource: 9dd26e71-f50e-44ca-9fae-226dbc05d7ff
   -------------------*/
/*!
 * Bootstrap v3.3.7 (http://getbootstrap.com)
 * Copyright 2011-2016 Twitter, Inc.
 * Licensed under MIT (https://github.com/twbs/bootstrap/blob/master/LICENSE)
 */
/* -------------------
BEGIN core-variables-mixins 
Sitecore Resource: b7e7d438-6af6-4188-9c02-8d47bdf84c71
   -------------------*/
/* -------------------
BEGIN variables-mixins 
Sitecore Resource: 4e0d219e-8f74-4ee8-b92e-d69c133f4266
   -------------------*/
/* -------------------
BEGIN core-inner-hero 
Sitecore Resource: 717b0cff-1168-41c1-a9ba-f61cbb79deaf
   -------------------*/

.hero-title {
  background: #018c5e;
  color: white;
  display: flex;
  flex-direction: column;
  justify-content: center;
  height: 87px;
}
@media (max-width:767px) {
  
}
.hero-title h1 {
  margin: 0;
  padding: 0;
  line-height: 1;
  font-size: 24px;
}
@media (max-width:991px) {
  .hero-title h1 {
    text-align: center;
  }
}
.inner-hero {
  background: #009966;
  background: linear-gradient(90deg, #009966 0%, #009966 75%, #88c354 100%);
  position: relative;
}
.inner-hero:before {
  content: "";
  position: absolute;
  bottom: 0;
  display: block;
  width: 100%;
  height: 100px;
  background: linear-gradient(185deg, rgba(19, 154, 104, 0) 0%, transparent 60%, rgba(0, 0, 0, 0.2) 100%);
}
.inner-hero .score-inner .hero-left {
  color: white;
}
@media (min-width:992px) {
  .inner-hero .score-inner .hero-left {
    height: 375px;
    display: flex;
    flex-direction: column;
    justify-content: center;
  }
}
.inner-hero .score-inner .hero-left h2,
.inner-hero .score-inner .hero-left .h2 {
  font-weight: 500;
  color: white;
}
@media (max-width:991px) {
  .inner-hero .score-inner .hero-left h2,
  .inner-hero .score-inner .hero-left .h2 {
    text-align: center;
    margin: 35px 0 25px;
  }
}
@media (max-width:991px) {
  .inner-hero .score-inner .hero-left p {
    text-align: center;
  }
}
@media (max-width:991px) {
  .inner-hero .score-inner .hero-left p.footnotes {
    text-align: left;
  }
}
.inner-hero .score-inner .hero-right {
  background: white;
  border-top: 14px solid #91c500;
  text-align: center;
  box-shadow: 0px 40px 40px rgba(0, 0, 0, 0.5);
  display: flex;
  flex-direction: column;
  justify-content: center;
}
@media (min-width:1200px) {
  .inner-hero .score-inner .hero-right {
    width: 445px;
  }
}
@media (min-width:992px) {
  .inner-hero .score-inner .hero-right {
    height: 420px;
    top: -38px;
    position: absolute;
    right: 15px;
  }
}
@media (max-width:991px) {
  .inner-hero .score-inner .hero-right {
    margin-right: 15px;
    margin-left: 15px;
    padding: 30px;
  }
}
.inner-hero .score-inner .hero-right:before {
  content: "";
  position: absolute;
  bottom: 0;
  left: 0;
  margin: 0 -15px;
  display: block;
  width: 100%;
  height: 100px;
  background: linear-gradient(185deg, rgba(19, 154, 104, 0) 0%, transparent 60%, rgba(0, 0, 0, 0.05) 100%);
}
.inner-hero .score-inner .hero-right img {
  width: 136px;
  height: auto;
  margin: 0 auto 24px;
}
@media (max-width:767px) {
  .inner-hero .score-inner .hero-right img {
    width: 100px;
  }
}
.inner-hero .score-inner .hero-right p {
  font-size: 22px;
  line-height: 1.35;
}
@media (max-width:991px) {
  .mechanism-of-action .hero-right img {
    margin-bottom: 12px !important;
  }
  .dosing-and-administration .inner-hero:before {
    background: -webkit-linear-gradient(90deg, rgba(225, 225, 225, 0.1) 100%, transparent 57%, rgba(0, 0, 0, 0.02) 50%, rgba(0, 0, 0, 0.03) 50%);
    height: 55%;
  }
}
/* -------------------
BEGIN formulary-coverage 
Sitecore Resource: cc0f8aa7-083d-4705-8de8-4e9b016a6b3d
   -------------------*/

div[class*=' section']:not(.section-references) .container {
  padding: 50px 0 30px;
}
@media (max-width:991px) {
  div[class*=' section']:not(.section-references) .container {
    padding: 0 15px;
  }
}
@media (max-width:767px) {
  div[class*=' section']:not(.section-references) .container {
    padding: 25px 15px 0px;
  }
}
.adult-table {
  margin: 50px 0;
}
@media (max-width:991px) {
  .adult-table {
    margin: 30px 0;
  }
}
.adult-table .adult-table-title {
  color: #009966;
  padding: 5px 20px;
}
.adult-table .adult-table-title h5 {
  text-transform: initial;
}
.adult-table .adult-table-body {
  display: flex;
  margin: 5px 0 0 0;
}
@media (max-width:991px) {
  .adult-table .adult-table-body {
    margin: -5px 0 0 0;
    flex-direction: column;
  }
}
.adult-table .adult-table-body .adult-table-body-part {
  border-right: 5px solid white;
  width: 70%;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part {
    border-right: none;
    width: 100%;
    display: flex;
    flex-direction: row;
    margin: 10px 0 0 0;
  }
}
.adult-table .adult-table-body .adult-table-body-part .head {
  background: #009966;
  color: white;
  min-height: 160px;
  text-align: center;
  margin: 0 0 5px;
  font-size: 16px;
  line-height: 1;
  padding: 10px;
  display: flex;
  align-items: center;
  justify-content: center;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .head {
    width: 50%;
    min-height: auto;
    padding: 20px 10px;
    margin: 0;
    text-align: left;
    justify-content: left;
  }
}
.adult-table .adult-table-body .adult-table-body-part .body {
  background: #e5e4e4;
  text-align: center;
  padding: 10px;
  min-height: 260px;
  display: flex;
  align-items: center;
  justify-content: center;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .body {
    width: 50%;
    min-height: auto;
    padding: 20px 10px;
  }
}
.adult-table .adult-table-body .adult-table-body-part .body-inner {
  display: flex;
  text-align: center;
  justify-content: space-evenly;
  width: 100%;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .body-inner {
    flex-direction: column;
    text-align: left;
  }
}
.adult-table .adult-table-body .adult-table-body-part .body-inner > div {
  width: 100%;
  display: flex;
  flex-direction: column;
  justify-content: center;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .body-inner > div {
    width: 100%;
    margin: 0 0 20px;
  }
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .body-inner > div:last-child {
    margin: 0 0 0px;
  }
}
.adult-table .adult-table-body .adult-table-body-part p {
  margin-bottom: 0;
  line-height: 1.3;
}
.adult-table .adult-table-body .adult-table-body-part .part-title {
  margin: 0 0 30px;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .part-title {
    position: absolute;
    top: 0px;
    background: #009966;
    left: 0;
    right: 0;
    width: 100%;
    margin: 0 auto;
    padding: 20px 10px;
    z-index: 1;
    border-bottom: 2px solid white;
    text-align: left;
  }
}
.adult-table .adult-table-body .adult-table-body-part .font-26 {
  font-size: 26px;
}
.adult-table .adult-table-body .adult-table-body-part small {
  font-size: 65%;
  position: relative;
  top: -7%;
}
.adult-table .adult-table-body .adult-table-body-part span {
  font-size: 17px;
  line-height: 1;
}
.adult-table .adult-table-body .adult-table-body-part .b-right {
  position: relative;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part .b-right::after {
    content: " ";
    position: absolute;
    border-bottom: 2px solid white;
    top: 15px;
    right: 0;
    width: 100%;
    height: 100%;
  }
}
.adult-table .adult-table-body .adult-table-body-part.data-divider {
  width: 100%;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part.data-divider {
    position: relative;
    padding: 60px 0 0 0;
  }
}
.adult-table .adult-table-body .adult-table-body-part.data-divider .head {
  flex-direction: column;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part.data-divider .head {
    justify-content: center;
  }
}
.adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner {
  position: relative;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner {
    text-align: left;
  }
}
.adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner:after {
  content: " ";
  position: absolute;
  width: 2px;
  height: 100%;
  background: white;
  left: 48%;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part.data-divider .head .body-inner:after {
    display: none;
  }
}
.adult-table .adult-table-body .adult-table-body-part.data-divider .body {
  position: relative;
}
.adult-table .adult-table-body .adult-table-body-part.data-divider .body:after {
  content: " ";
  position: absolute;
  width: 2px;
  height: 80%;
  left: 48%;
  background: white;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part.data-divider .body:after {
    display: none;
  }
}
.adult-table .adult-table-body .adult-table-body-part:last-child {
  border-right: none;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part:last-child {
    position: relative;
    padding: 60px 0 0 0;
  }
}
.adult-table .adult-table-body .adult-table-body-part:last-child .head {
  display: flex;
  flex-direction: column;
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part:last-child .head {
    margin: 0;
    justify-content: center;
  }
}
@media (max-width:991px) {
  .adult-table .adult-table-body .adult-table-body-part:last-child .head .body-inner {
    text-align: left;
  }
}
@media (max-width:991px) and (min-width:768px) {
  .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right {
    margin: 30px 0 30px;
  }
}
@media (max-width:767px) {
  .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right {
    margin: 15px 0 45px;
  }
}
@media (max-width:991px) and (min-width:768px) {
  .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right::after {
    top: 20px;
  }
}
@media (max-width:767px) {
  .adult-table .adult-table-body .adult-table-body-part.column5 .head .body-inner .b-right::after {
    top: 40px;
  }
}
@media (max-width:991px) {
  .adult-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
    padding: 25px 0 20px;
    border-bottom: 2px solid white;
    margin: 0 0 20px;
  }
  .adult-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right:after {
    display: none;
  }
  .adult-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .body .b-right {
    margin: 0 0 35px;
  }
}
@media (min-width:992px) {
  .adolescent-study-design div.section-content .container {
    padding: 50px 0 0 !important;
  }
}
.adolescent-study-design .adult-table .adult-table-body .adult-table-body-part .body {
  min-height: 340px;
}
@media (max-width:991px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part .body {
    min-height: auto;
  }
}
@media (max-width:991px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
    padding: 25px 0 20px;
    border-bottom: 2px solid white;
    margin: 0 0 20px;
  }
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right:after {
    display: none;
  }
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .body .b-right {
    margin: 0 0 35px;
  }
}
@media (max-width:767px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
    padding: 10px 0 35px;
    margin: 0 0 20px;
  }
}
@media (min-width:992px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column1 {
    width: 50%;
  }
}
@media (min-width:992px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column2 {
    width: 50%;
  }
}
@media (min-width:992px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column3 {
    width: 100%;
  }
}
@media (min-width:992px) {
  .adolescent-study-design .adult-table .adult-table-body .adult-table-body-part.column6 {
    width: 60%;
  }
}
@media (min-width:992px) {
  .children-study-designs div.section-content .container {
    padding: 50px 0 0 !important;
  }
}
@media (min-width:992px) {
  .children-study-designs div.section-content .container h2 + p {
    margin-bottom: 30px;
  }
}
@media (min-width:992px) {
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column3 {
    width: 100%;
  }
}
@media (max-width:991px) {
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column4 {
    position: relative;
    padding: 60px 0 0 0;
  }
}
.children-study-designs .adult-table .adult-table-body .adult-table-body-part.column4 .head {
  display: flex;
  flex-direction: column;
}
.children-study-designs .adult-table .adult-table-body .adult-table-body-part.column4 .head .part-title {
  margin: 0 0 20px;
}
@media (max-width:991px) {
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
    padding: 10px 0 35px;
    border-bottom: 2px solid white;
    margin: 0 0 20px;
  }
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right:after {
    display: none;
  }
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .body .b-right {
    margin: 0 0 35px;
  }
}
@media (max-width:767px) {
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part.column5.data-divider .head .b-right {
    padding: 10px 0 35px;
  }
}
.children-study-designs .adult-table .adult-table-body .adult-table-body-part .body {
  min-height: 370px;
}
@media (max-width:991px) {
  .children-study-designs .adult-table .adult-table-body .adult-table-body-part .body {
    min-height: auto;
  }
}
.treatment-effects {
  display: flex;
  text-align: center;
  margin: 60px 0 40px;
  justify-content: center;
}
@media (max-width:991px) {
  .treatment-effects {
    flex-direction: row;
    flex-wrap: wrap;
    justify-content: space-evenly;
    margin-bottom: 10px;
  }
}
.treatment-effects > div {
  margin: 0 60px 0 0;
}
.treatment-effects > div p {
  margin: 15px 0 0;
}
@media (max-width:991px) {
  .treatment-effects > div {
    margin: 0 10px 40px 0;
  }
}
.btn.btn-lime-arrow {
  padding: 30px 0;
  font-size: 17px;
}
.btn.btn-lime-arrow.pt-15 {
  padding-top: 15px;
}
.btn-group .btn.btn-lime-arrow {
  padding: 0;
  margin-bottom: 25px;
}
.btn-group + p {
  margin-bottom: 25px;
}
@media (max-width:991px) {
  .btn-group.m-block {
    display: block;
  }
  .btn-group.m-block .btn.btn-lime-arrow:after {
    margin-left: 5px;
  }
}
sup.symbol.adjust {
  top: 0.5em;
  left: -5px;
}
@media (max-width:991px) {
  sup.symbol.adjust {
    left: -11px;
  }
}
sup.symbol.adjust1 {
  top: 0.5em;
  left: -10px;
}
@media (max-width:991px) {
  sup.symbol.adjust1 {
    left: -19px;
  }
}
@media (max-width:991px) {
  .m-text-center .btn.btn-lime-arrow {
    text-align: center;
  }
}
.my-50p {
  margin: 50px 0;
}
@media (max-width:991px) {
  .my-50p {
    margin: 0px 0 15px 0;
  }
}
@media (max-width:991px) {
  .adult-table .font-26,
  .adult-table-body-part .font-26 {
    text-align: center;
  }
  .adult-table-body .column2 .head {
    align-items: start !important;
  }
  .adult-table-body .column2 sup {
    left: 1px;
    top: 22px;
  }
  .adult-table-body .column1 .head {
    align-items: start !important;
  }
  .adult-table-body .column1 sup {
    left: -16px;
    top: 22px;
  }
  .adult-table-body .column3 .head {
    align-items: start !important;
  }
  .adult-table-body .column3 sup {
    top: 3px;
  }
  .adult-table .adult-table-body .adult-table-body-part.column2 {
    margin-top: 2px;
  }
  .adult-table .adult-table-body .adult-table-body-part.column3 {
    margin-top: 2px;
  }
  sup.symbol.efficacy-sup {
    top: -0.3em;
  }
  .adult-table-body sup.symbol.dosing-sup {
    top: -0.6em;
  }
}
@media (min-width:768px) {
  .footnotes:not(:last-of-type) {
    padding-bottom: 10px;
  }
}
.study-designs div.section-content .container h2,
.study-designs div.section-content .container .h2 {
  line-height: 1.2;
}
@media (max-width:767px) {
  .pb-30-mob {
    padding-bottom: 30px;
  }
}