Pruritus NRS assesses the average itch intensity over the previous 24 hours⁴

It is a patient-reported measure that uses a 0- to 10-point scale, with which patients are asked:

“On a scale of 0 to 10, how would you rate your itch overall (on average) during the previous 24 hours?”

A reduction of at least 4 points in pruritus NRS from baseline is a clinically meaningful change.¹